Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells

Shigella, the causative agent of bacillary dysentery, is capable of directing its movement within host cells by exploiting actin dynamics. The VirG protein expressed at one pole of the bacterium can recruit neural Wiskott-Aldrich syndrome protein (N-WASP), a downstream effector of Cdc42. Here, we sh...

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Bibliografiske detaljer
Main Authors: Suzuki, Toshihiko, Mimuro, Hitomi, Miki, Hiroaki, Takenawa, Tadaomi, Sasaki, Takuya, Nakanishi, Hiroyuki, Takai, Yoshimi, Sasakawa, Chihiro
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213524/
https://ncbi.nlm.nih.gov/pubmed/10839806
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