Homologous recombination-deficient tumors are hyper-dependent on POLQ-mediated repair

Lignende værker

• Homologous recombination deficiency: Exploiting the fundamental vulnerability of ovarian cancer
  af: Konstantinopoulos, Panagiotis A., et al.
  Udgivet: (2015)
• A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance
  af: Ceccaldi, Raphael, et al.
  Udgivet: (2015)
• Replication blocking lesions present a unique substrate for homologous recombination
  af: Ward, Jordan D, et al.
  Udgivet: (2007)
• Inhibition of homologous recombination by the PCNA-interacting protein PARI
  af: Moldovan, George-Lucian, et al.
  Udgivet: (2011)
• MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability
  af: Choi, Young Eun, et al.
  Udgivet: (2014)