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Replication blocking lesions present a unique substrate for homologous recombination
Homologous recombination (HR) plays a critical role in the restart of blocked replication forks, but how this is achieved remains poorly understood. We show that mutants in the single Rad51 paralog in Caenorhabditis elegans, rfs-1, permit discrimination between HR substrates generated at DNA double-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933397/ https://ncbi.nlm.nih.gov/pubmed/17611606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601766 |
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