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A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance

Platinum and PARP inhibitor (PARPi) sensitivity commonly coexist in epithelial ovarian cancer (EOC) due to the high prevalence of alterations in the homologous recombination (HR) DNA repair pathway that confer sensitivity to both drugs. In this report, we describe a unique subset of EOC with alterat...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Ceccaldi, Raphael, O'Connor, Kevin W., Mouw, Kent W., Li, Adam Y., Matulonis, Ursula A., D'Andrea, Alan D., Konstantinopoulos, Panagiotis A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416405/
https://ncbi.nlm.nih.gov/pubmed/25634215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2593
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