Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.
To develop a system for overexpressing genes in the vascular wall, we created transgenic mice using the reporter gene luciferase and the murine preproendothelin-1 promoter. In vitro analysis suggested that the murine 5'-flanking region contained endothelial-specific elements in a 5.9-kb fragment. Fi...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117784 |
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