Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.

To develop a system for overexpressing genes in the vascular wall, we created transgenic mice using the reporter gene luciferase and the murine preproendothelin-1 promoter. In vitro analysis suggested that the murine 5'-flanking region contained endothelial-specific elements in a 5.9-kb fragment. Fi...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Harats, D, Kurihara, H, Belloni, P, Oakley, H, Ziober, A, Ackley, D, Cain, G, Kurihara, Y, Lawn, R, Sigal, E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC441473/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7883980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117784
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