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Syntheses and Radiosyntheses of Two Carbon-11 Labeled Potent and Selective Radioligands for Imaging Vesicular Acetylcholine Transporter
PURPOSE: The vesicular acetylcholine transporter (VAChT) is a specific biomarker for imaging presynaptic cholinergic neurons. The syntheses and C-11 labeling of two potent enantiopure VAChT inhibitors are reported here. PROCEDURES: Two VAChT inhibitors, (±)-2 and (±)-6, were successfully synthesized...
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| Publicado no: | Mol Imaging Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4414325/ https://ncbi.nlm.nih.gov/pubmed/24875230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0748-x |
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