Syntheses and Radiosyntheses of Two Carbon-11 Labeled Potent and Selective Radioligands for Imaging Vesicular Acetylcholine Transporter

PURPOSE: The vesicular acetylcholine transporter (VAChT) is a specific biomarker for imaging presynaptic cholinergic neurons. The syntheses and C-11 labeling of two potent enantiopure VAChT inhibitors are reported here. PROCEDURES: Two VAChT inhibitors, (±)-2 and (±)-6, were successfully synthesized...

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Bibliografiska uppgifter
I publikationen:Mol Imaging Biol
Huvudupphovsmän: Padakanti, Prashanth K., Zhang, Xiang, Li, Junfeng, Parsons, Stanley M., Perlmutter, Joel S., Tu, Zhude
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414325/
https://ncbi.nlm.nih.gov/pubmed/24875230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0748-x
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