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Genetically Engineered Humanized Mouse Models for Preclinical Antibody Studies

The use of genetic engineering has vastly improved our capabilities to create animal models relevant in preclinical research. With the recent advances in gene-editing technologies, it is now possible to very rapidly create highly tunable mouse models as needs arise. Here, we provide an overview of g...

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Detalhes bibliográficos
Publicado no:BioDrugs
Main Authors: Proetzel, Gabriele, Wiles, Michael V., Roopenian, Derry C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414315/
https://ncbi.nlm.nih.gov/pubmed/24150980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-013-0071-0
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