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Genetically Engineered Mouse Models of Brain Cancer and the Promise of Preclinical Testing

Recent improvements in the understanding of brain tumor biology have opened the door to a number of rational therapeutic strategies targeting distinct oncogenic pathways. The successful translation of such “designer drugs” to clinical application depends heavily on effective and expeditious screenin...

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Autores principales: Huse, Jason T., Holland, Eric C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659383/
https://ncbi.nlm.nih.gov/pubmed/19076778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00234.x
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