Reduced Cortisol Metabolism during Critical Illness

BACKGROUND: Critical illness is often accompanied by hypercortisolemia, which has been attributed to stress-induced activation of the hypothalamic–pituitary–adrenal axis. However, low corticotropin levels have also been reported in critically ill patients, which may be due to reduced cortisol metabo...

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Udgivet i:N Engl J Med
Main Authors: Boonen, Eva, Vervenne, Hilke, Meersseman, Philippe, Andrew, Ruth, Mortier, Leen, Declercq, Peter E., Vanwijngaerden, Yoo-Mee, Spriet, Isabel, Wouters, Pieter J., Perre, Sarah Vander, Langouche, Lies, Vanhorebeek, Ilse, Walker, Brian R., Van den Berghe, Greet
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413428/
https://ncbi.nlm.nih.gov/pubmed/23506003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1214969
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