Intensive insulin therapy protects the endothelium of critically ill patients

The vascular endothelium controls vasomotor tone and microvascular flow and regulates trafficking of nutrients and biologically active molecules. When endothelial activation is excessive, compromised microcirculation and subsequent cellular hypoxia contribute to the risk of organ failure. We hypothe...

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Main Authors: Langouche, Lies, Vanhorebeek, Ilse, Vlasselaers, Dirk, Vander Perre, Sarah, Wouters, Pieter J., Skogstrand, Kristin, Hansen, Troels K., Van den Berghe, Greet
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180545/
https://ncbi.nlm.nih.gov/pubmed/16075063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25385
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