The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis

BACKGROUND: Sepsis is typically hallmarked by high plasma (free) cortisol and suppressed cortisol breakdown, while plasma adrenocorticotropic hormone (ACTH) is not increased, referred to as ‘ACTH–cortisol dissociation.’ We hypothesized that sepsis acutely activates the hypothalamus to generate, via...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Crit Care
Egile Nagusiak: Téblick, Arno, Vander Perre, Sarah, Pauwels, Lies, Derde, Sarah, Van Oudenhove, Tim, Langouche, Lies, Van den Berghe, Greet
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885358/
https://ncbi.nlm.nih.gov/pubmed/33593393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-021-03475-y
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