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The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis
BACKGROUND: Sepsis is typically hallmarked by high plasma (free) cortisol and suppressed cortisol breakdown, while plasma adrenocorticotropic hormone (ACTH) is not increased, referred to as ‘ACTH–cortisol dissociation.’ We hypothesized that sepsis acutely activates the hypothalamus to generate, via...
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| Опубликовано в: : | Crit Care |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885358/ https://ncbi.nlm.nih.gov/pubmed/33593393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-021-03475-y |
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