OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?

Background: Septic patients often develop muscle weakness, contributing to ICU morbidity and mortality. We recently observed that obese septic mice and patients do not develop such weakness, explained by increased lipolysis and hepatic conversion of fatty acids into the ketone bodies. Furthermore, i...

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Vydáno v:J Endocr Soc
Hlavní autoři: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Vander Perre, Sarah, Pauwels, Lies, Van den Berghe, Greet, Langouche, Lies
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Adipose Tissue, Appetite, and Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555032/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR20-6
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