OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?

Background: Septic patients often develop muscle weakness, contributing to ICU morbidity and mortality. We recently observed that obese septic mice and patients do not develop such weakness, explained by increased lipolysis and hepatic conversion of fatty acids into the ketone bodies. Furthermore, i...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Vander Perre, Sarah, Pauwels, Lies, Van den Berghe, Greet, Langouche, Lies
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Adipose Tissue, Appetite, and Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555032/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR20-6
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