Altered cholesterol homeostasis in critical illness-induced muscle weakness: effect of exogenous 3-hydroxybutyrate

BACKGROUND: Muscle weakness is a complication of critical illness which hampers recovery. In critically ill mice, supplementation with the ketone body 3-hydroxybutyrate has been shown to improve muscle force and to normalize illness-induced hypocholesterolemia. We hypothesized that altered cholester...

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Veröffentlicht in:Crit Care
Hauptverfasser: Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Vander Perre, Sarah, Derese, Inge, Van Veldhoven, Paul P., Ghesquière, Bart, Van den Berghe, Greet, Langouche, Lies
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8285799/
https://ncbi.nlm.nih.gov/pubmed/34274000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-021-03688-1
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