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OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?

Background: Septic patients often develop muscle weakness, contributing to ICU morbidity and mortality. We recently observed that obese septic mice and patients do not develop such weakness, explained by increased lipolysis and hepatic conversion of fatty acids into the ketone bodies. Furthermore, i...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Vander Perre, Sarah, Pauwels, Lies, Van den Berghe, Greet, Langouche, Lies
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6555032/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR20-6
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