Reduced nocturnal ACTH-driven cortisol secretion during critical illness

Recently, during critical illness, cortisol metabolism was found to be reduced. We hypothesize that such reduced cortisol breakdown may suppress pulsatile ACTH and cortisol secretion via feedback inhibition. To test this hypothesis, nocturnal ACTH and cortisol secretory profiles were constructed by...

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Detalhes bibliográficos
Main Authors: Boonen, Eva, Meersseman, Philippe, Vervenne, Hilke, Meyfroidt, Geert, Guïza, Fabian, Wouters, Pieter J., Veldhuis, Johannes D., Van den Berghe, Greet
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989736/
https://ncbi.nlm.nih.gov/pubmed/24569590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00009.2014
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