Endogenous ACTH Concentration-Cortisol Secretion Dose Analysis Unmasks Decreased ACTH Potency in Cushing's Disease with Restoration after Successful Pituitary Adenomectomy

BACKGROUND: The relationship between circulating ACTH levels and cortisol secretion in Cushing's disease is not precisely known. HYPOTHESIS: Chronic ACTH hyperstimulation leads to decreased adrenal potency and is restored after normalization of ACTH secretion. SUBJECTS: Subjects included 20 pat...

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Bibliographic Details
Main Authors: Roelfsema, Ferdinand, Keenan, Daniel M., Veldhuis, Johannes D.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
Endocrine Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410358/
https://ncbi.nlm.nih.gov/pubmed/21917875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1878
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