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Reduced nocturnal ACTH-driven cortisol secretion during critical illness

Recently, during critical illness, cortisol metabolism was found to be reduced. We hypothesize that such reduced cortisol breakdown may suppress pulsatile ACTH and cortisol secretion via feedback inhibition. To test this hypothesis, nocturnal ACTH and cortisol secretory profiles were constructed by...

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Главные авторы: Boonen, Eva, Meersseman, Philippe, Vervenne, Hilke, Meyfroidt, Geert, Guïza, Fabian, Wouters, Pieter J., Veldhuis, Johannes D., Van den Berghe, Greet
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989736/
https://ncbi.nlm.nih.gov/pubmed/24569590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00009.2014
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