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Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens
Sterol 14α-demethylase is a validated and an attractive drug target in human protozoan parasites. Pharmacological inactivation of this important enzyme has proven very effective against fungal infections, and it is a target that is being exploited for new antitrypanosomal and antileishmanial chemoth...
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| Publié dans: | Springerplus |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4410773/ https://ncbi.nlm.nih.gov/pubmed/25932361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-679 |
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