Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis

Chemokine gradient formation requires multiple processes that include ligand secretion and diffusion, receptor binding and internalization, and immobilization of ligand to surfaces. To understand how these events dynamically shape gradients and influence ensuing cell chemotaxis, we built a multi-sca...

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Bibliographic Details
Published in:PLoS One
Main Authors: Chang, S. Laura, Cavnar, Stephen P., Takayama, Shuichi, Luker, Gary D., Linderman, Jennifer J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409393/
https://ncbi.nlm.nih.gov/pubmed/25909600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123450
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