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Cell, Isoform, and Environment Factors Shape Gradients and Modulate Chemotaxis

Chemokine gradient formation requires multiple processes that include ligand secretion and diffusion, receptor binding and internalization, and immobilization of ligand to surfaces. To understand how these events dynamically shape gradients and influence ensuing cell chemotaxis, we built a multi-sca...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chang, S. Laura, Cavnar, Stephen P., Takayama, Shuichi, Luker, Gary D., Linderman, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409393/
https://ncbi.nlm.nih.gov/pubmed/25909600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123450
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