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Microfluidic source-sink model reveals effects of biophysically distinct CXCL12-isoforms in breast cancer chemotaxis

Chemokines critically regulate chemotaxis in normal and pathologic states, but there is limited understanding of how multicellular interactions generate gradients needed for cell migration. Previous studies of chemotaxis of CXCR4+ cells toward chemokine CXCL12 suggest the requirement of cells expres...

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Detalles Bibliográficos
Autores principales: Cavnar, S.P., Ray, P., Moudgil, P., Chang, S.L., Luker, K.E., Linderman, J.J., S.Takayama, Luker, G.D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034763/
https://ncbi.nlm.nih.gov/pubmed/24675873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ib00015c
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