Microfluidic source-sink model reveals effects of biophysically distinct CXCL12-isoforms in breast cancer chemotaxis

Chemokines critically regulate chemotaxis in normal and pathologic states, but there is limited understanding of how multicellular interactions generate gradients needed for cell migration. Previous studies of chemotaxis of CXCR4+ cells toward chemokine CXCL12 suggest the requirement of cells expres...

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Bibliografiske detaljer
Main Authors: Cavnar, S.P., Ray, P., Moudgil, P., Chang, S.L., Luker, K.E., Linderman, J.J., S.Takayama, Luker, G.D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034763/
https://ncbi.nlm.nih.gov/pubmed/24675873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ib00015c
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