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Microfluidic source-sink model reveals effects of biophysically distinct CXCL12-isoforms in breast cancer chemotaxis

Chemokines critically regulate chemotaxis in normal and pathologic states, but there is limited understanding of how multicellular interactions generate gradients needed for cell migration. Previous studies of chemotaxis of CXCR4+ cells toward chemokine CXCL12 suggest the requirement of cells expres...

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Hlavní autoři: Cavnar, S.P., Ray, P., Moudgil, P., Chang, S.L., Luker, K.E., Linderman, J.J., S.Takayama, Luker, G.D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034763/
https://ncbi.nlm.nih.gov/pubmed/24675873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ib00015c
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