Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro

Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources. Nucleoside hydrolases release purines from nucleosides and are drug targets for anti-leishmanial drugs, absen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Freitas, Elisangela Oliveira, Nico, Dirlei, Guan, Rong, Meyer-Fernandes, José Roberto, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409337/
https://ncbi.nlm.nih.gov/pubmed/25909893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124183
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