Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis

BACKGROUND: Immucillins ImmA (IA), ImmH (IH) and SerMe-ImmH (SMIH) are synthetic deazapurine nucleoside analogues that inhibit Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis multiplication in vitro without macrophage toxicity. Immucillins are compared to the Glucantime standard dru...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Autores principales: Freitas, Elisangela Oliveira, Nico, Dirlei, Alves-Silva, Marcus Vinícius, Morrot, Alexandre, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689457/
https://ncbi.nlm.nih.gov/pubmed/26701750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004297
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