Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro

Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources. Nucleoside hydrolases release purines from nucleosides and are drug targets for anti-leishmanial drugs, absen...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Freitas, Elisangela Oliveira, Nico, Dirlei, Guan, Rong, Meyer-Fernandes, José Roberto, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409337/
https://ncbi.nlm.nih.gov/pubmed/25909893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124183
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