Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro

Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources. Nucleoside hydrolases release purines from nucleosides and are drug targets for anti-leishmanial drugs, absen...

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Publicado en:PLoS One
Autores principales: Freitas, Elisangela Oliveira, Nico, Dirlei, Guan, Rong, Meyer-Fernandes, José Roberto, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409337/
https://ncbi.nlm.nih.gov/pubmed/25909893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124183
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