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Bicarbonate Modulates Photoreceptor Guanylate Cyclase (ROS-GC) Catalytic Activity
By generating the second messenger cGMP in retinal rods and cones, ROS-GC plays a central role in visual transduction. Guanylate cyclase-activating proteins (GCAPs) link cGMP synthesis to the light-induced fall in [Ca(2+)](i) to help set absolute sensitivity and assure prompt recovery of the respons...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409265/ https://ncbi.nlm.nih.gov/pubmed/25767116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.650408 |
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