Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones

The membrane guanylate cyclase, ROS-GC, that synthesizes cyclic GMP for use as a second messenger for visual transduction in retinal rods and cones, is stimulated by bicarbonate. Bicarbonate acts directly on ROS-GC1, because it enhanced the enzymatic activity of a purified, recombinant fragment of b...

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Bibliografske podrobnosti
izdano v:eNeuro
Main Authors: Makino, Clint L., Duda, Teresa, Pertzev, Alexandre, Isayama, Tomoki, Geva, Polina, Sandberg, Michael A., Sharma, Rameshwar K.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
New Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378327/
https://ncbi.nlm.nih.gov/pubmed/30783616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0393-18.2019
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