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S100B Serves as a Ca(2+) Sensor for ROS-GC1 Guanylate Cyclase in Cones but Not in Rods of the Murine Retina
Rod outer segment membrane guanylate cyclase (ROS-GC1) is a bimodal Ca(2+) signal transduction switch. Lowering [Ca(2+)](i) from 200 to 20 nM progressively turns it “ON” as does raising [Ca(2+)](i) from 500 to 5000 nM. The mode operating at lower [Ca(2+)](i) plays a vital role in phototransduction i...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
S. Karger AG
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434333/ https://ncbi.nlm.nih.gov/pubmed/22508049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000338496 |
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