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CO(2)/bicarbonate modulates cone photoreceptor ROS-GC1 and restores its CORD6-linked catalytic activity
This study with recombinant reconstituted system mimicking the cellular conditions of the native cones, documents that photoreceptor ROS-GC1 is modulated by gaseous CO(2). Mechanistically, CO(2) is sensed by carbonic anhydrase (CAII), generates bicarbonate that, in turn, directly targets the core ca...
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| Udgivet i: | Mol Cell Biochem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687076/ https://ncbi.nlm.nih.gov/pubmed/29427171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-018-3317-9 |
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