טוען...
Systematic Profiling of Poly(A)+ Transcripts Modulated by Core 3’ End Processing and Splicing Factors Reveals Regulatory Rules of Alternative Cleavage and Polyadenylation
Alternative cleavage and polyadenylation (APA) results in mRNA isoforms containing different 3’ untranslated regions (3’UTRs) and/or coding sequences. How core cleavage/polyadenylation (C/P) factors regulate APA is not well understood. Using siRNA knockdown coupled with deep sequencing, we found tha...
שמור ב:
הוצא לאור ב: | PLoS Genet |
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Main Authors: | , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Public Library of Science
2015
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407891/ https://ncbi.nlm.nih.gov/pubmed/25906188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005166 |
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