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Binary and ternary combinations of anti-HIV protease inhibitors: effect on gene expression and functional activity of CYP3A4 and efflux transporters

BACKGROUND: The purpose of this study is to identify the effect of binary and ternary combinations of anti-HIV protease inhibitors (PIs) on the expression of metabolizing enzyme (CYP3A4) and efflux transporters [multidrug resistance-associated protein 2 (MRP2), P-glycoprotein (P-gp) and breast cance...

詳細記述

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書誌詳細
出版年:Drug Metabol Drug Interact
主要な著者: Kwatra, Deep, Vadlapudi, Aswani Dutt, Vadlapatla, Ramya Krishna, Khurana, Varun, Pal, Dhananjay, Mitra, Ashim K.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407648/
https://ncbi.nlm.nih.gov/pubmed/24399676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/dmdi-2013-0056
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