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Molecular Expression and Functional Activity of Efflux and Influx Transporters in Hypoxia Induced Retinal Pigment Epithelial Cells

A decrease in tissue oxygen levels (aka hypoxia) mediates a number of vascular retinal diseases. Despite introduction of novel therapeutics, treatment of retinal disorders remains challenging, possibly due to complex nature of hypoxia signaling. To date, the differential effect of hypoxia on express...

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Bibliographic Details
Main Authors: Vadlapatla, Ramya, Vadlapudi, Aswani Dutt, Ponnaluri, VK Chaithanya, Pal, Dhananjay, Mukherji, Mridul, Mitra, Ashim K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761793/
https://ncbi.nlm.nih.gov/pubmed/23827654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2013.06.044
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