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Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance

The purpose of the study is to screen the interactions of fourth generation fluoroquinolone-gatifloxacin with efflux pumps i.e. P-gp, MRP2 and BCRP. Mechanism of gatifloxacin interaction with efflux transporters may explain its acquired resistance. Such clarification may lead to the development of s...

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Huvudupphovsmän: Kwatra, Deep, Vadlapatla, Ramya Krishna, Vadlapudi, Aswani Dutt, Pal, Dhananjay, Mitra, Ashim K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902587/
https://ncbi.nlm.nih.gov/pubmed/20573570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.05.027
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