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Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance
The purpose of the study is to screen the interactions of fourth generation fluoroquinolone-gatifloxacin with efflux pumps i.e. P-gp, MRP2 and BCRP. Mechanism of gatifloxacin interaction with efflux transporters may explain its acquired resistance. Such clarification may lead to the development of s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902587/ https://ncbi.nlm.nih.gov/pubmed/20573570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.05.027 |
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