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Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin
Fluoroquinolones are broad spectrum antibiotics widely indicated in the treatment of both human and animal diseases. The primary objective of this study was to assess short and long term affinity of gemifloxacin towards efflux transporters (P-gp, MRP2) and nuclear hormone receptor (PXR). Uptake and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3195835/ https://ncbi.nlm.nih.gov/pubmed/21864659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2011.08.009 |
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