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Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells

In this chapter, we describe a gene-specific quantitative PCR (QPCR)-based assay for the measurement of DNA damage, using amplification of long DNA targets. This assay has been used extensively to measure the integrity of both nuclear and mitochondrial genomes exposed to different genotoxins and has...

詳細記述

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書誌詳細
出版年:Methods Mol Biol
主要な著者: Furda, Amy, Santos, Janine H., Meyer, Joel N., Van Houten, Bennett
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407362/
https://ncbi.nlm.nih.gov/pubmed/24623245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-739-6_31
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