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Quantitative PCR-Based Measurement of Nuclear and Mitochondrial DNA Damage and Repair in Mammalian Cells

In this chapter, we describe a gene-specific quantitative PCR (QPCR)-based assay for the measurement of DNA damage, using amplification of long DNA targets. This assay has been used extensively to measure the integrity of both nuclear and mitochondrial genomes exposed to different genotoxins and has...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Methods Mol Biol
Egile Nagusiak: Furda, Amy, Santos, Janine H., Meyer, Joel N., Van Houten, Bennett
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407362/
https://ncbi.nlm.nih.gov/pubmed/24623245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-739-6_31
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