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Quantitative PCR analysis of diepoxybutane and epihalohydrin damage to nuclear versus mitochondrial DNA

The bifunctional alkylating agents diepoxybutane (DEB) and epichlorohydrin (ECH) are linked to the elevated incidence of certain cancers among workers in the synthetic polymer industry. Both compounds form interstrand cross-links within duplex DNA, an activity suggested to contribute to their cytoto...

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Bibliografiske detaljer
Main Authors: LaRiviere, Frederick J., Newman, Adam G., Watts, Megan L., Bradley, Sharonda Q., Juskewitch, Justin E., Greenwood, Paul G., Millard, Julie T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727856/
https://ncbi.nlm.nih.gov/pubmed/19428380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.02.004
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