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Evidence against a role of P-glycoprotein in the clearance of the Alzheimer’s disease Aβ(1–42) peptides

It has been proposed that the amyloid-β peptides (Aβ) cause the neuronal degeneration in the Alzheimer’s disease brain. An imbalance between peptide production at the neuronal level and their elimination across the blood–brain–barrier (BBB) results in peptide accumulation inside the brain. The ident...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Bello, Ivan, Salerno, Milena
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406933/
https://ncbi.nlm.nih.gov/pubmed/25591827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-014-0566-8
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