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A Role for P-Glycoprotein in Clearance of Alzheimer Amyloid β-Peptide from the Brain

Most data indicates that Alzheimer’s disease involves an accumulation of amyloid β-peptide (Aβ) in the CNS and that sporadic cases arise from a deficiency in Aβ clearance. Considerable attention has been given to mechanisms by which Aβ might be transported between the brain and blood, and evidence s...

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Détails bibliographiques
Publié dans:Curr Alzheimer Res
Auteurs principaux: Wei, Wang, Bodles-Brakhop, Angela M., Barger, Steven W.
Format: Artigo
Langue:Inglês
Publié: 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102249/
https://ncbi.nlm.nih.gov/pubmed/26971931
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