MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier

Amyloid‐β (Aβ) is the major component of the insoluble amyloid plaques that accumulate intracerebrally in patients with Alzheimer’s disease (AD). It has been suggested that MDR1‐P‐glycoprotein (ABCB1, P‐gp) plays a substantial role in the elimination of Aβ from the brain. In the present study, MDR1‐...

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Enregistré dans:
Détails bibliographiques
Publié dans:Brain Pathol
Auteurs principaux: Kuhnke, Diana, Jedlitschky, Gabriele, Grube, Markus, Krohn, Markus, Jucker, Mathias, Mosyagin, Igor, Cascorbi, Ingolf, Walker, Lary C., Kroemer, Heyo K., Warzok, Rolf W., Vogelgesang, Silke
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2007
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095502/
https://ncbi.nlm.nih.gov/pubmed/17610523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2007.00075.x
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