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MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier

Amyloid‐β (Aβ) is the major component of the insoluble amyloid plaques that accumulate intracerebrally in patients with Alzheimer’s disease (AD). It has been suggested that MDR1‐P‐glycoprotein (ABCB1, P‐gp) plays a substantial role in the elimination of Aβ from the brain. In the present study, MDR1‐...

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Bibliografski detalji
Izdano u:Brain Pathol
Glavni autori: Kuhnke, Diana, Jedlitschky, Gabriele, Grube, Markus, Krohn, Markus, Jucker, Mathias, Mosyagin, Igor, Cascorbi, Ingolf, Walker, Lary C., Kroemer, Heyo K., Warzok, Rolf W., Vogelgesang, Silke
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095502/
https://ncbi.nlm.nih.gov/pubmed/17610523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2007.00075.x
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