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MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier

Amyloid‐β (Aβ) is the major component of the insoluble amyloid plaques that accumulate intracerebrally in patients with Alzheimer’s disease (AD). It has been suggested that MDR1‐P‐glycoprotein (ABCB1, P‐gp) plays a substantial role in the elimination of Aβ from the brain. In the present study, MDR1‐...

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Foilsithe in:Brain Pathol
Main Authors: Kuhnke, Diana, Jedlitschky, Gabriele, Grube, Markus, Krohn, Markus, Jucker, Mathias, Mosyagin, Igor, Cascorbi, Ingolf, Walker, Lary C., Kroemer, Heyo K., Warzok, Rolf W., Vogelgesang, Silke
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Publishing Ltd 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095502/
https://ncbi.nlm.nih.gov/pubmed/17610523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2007.00075.x
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