Expression and Localization of the Multidrug Resistance Protein 5 (MRP5/ABCC5), a Cellular Export Pump for Cyclic Nucleotides, in Human Heart

The multidrug resistance protein 5 (MRP5/ABCC5) has been recently identified as cellular export pump for cyclic nucleotides with 3′,5′-cyclic GMP (cGMP) as a high-affinity substrate. In view of the important role of cGMP for cardiovascular function, expression of this transport protein in human hear...

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Autori principali: Dazert, Peter, Meissner, Konrad, Vogelgesang, Silke, Heydrich, Björn, Eckel, Lothar, Böhm, Michael, Warzok, Rolf, Kerb, Reinhold, Brinkmann, Ulrich, Schaeffeler, Elke, Schwab, Matthias, Cascorbi, Ingolf, Jedlitschky, Gabriele, Kroemer, Heyo K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2003
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868287/
https://ncbi.nlm.nih.gov/pubmed/14507663
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