Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice

Neurovascular dysfunction is an important component of Alzheimer's disease, leading to reduced clearance across the blood-brain barrier and accumulation of neurotoxic β-amyloid (Aβ) peptides in the brain. It has been shown that the ABC transport protein P-glycoprotein (P-gp, ABCB1) is involved...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Brenn, Anja, Grube, Markus, Peters, Michele, Fischer, Andrea, Jedlitschky, Gabriele, Kroemer, Heyo K., Warzok, Rolf W., Vogelgesang, Silke
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109772/
https://ncbi.nlm.nih.gov/pubmed/21660212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/690121
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares