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Clearance of amyloid-β peptide across the blood-brain barrier: Implication for therapies in Alzheimer’s disease

The main receptors for amyloid-beta peptide (Aβ) transport across the blood-brain barrier (BBB) from brain to blood and blood to brain are low-density lipoprotein receptor related protein-1 (LRP1) and receptor for advanced glycation end products (RAGE), respectively. In normal human plasma a soluble...

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Detalhes bibliográficos
Main Authors: Deane, R, Bell, RD, Sagare, A, Zlokovic, BV
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872930/
https://ncbi.nlm.nih.gov/pubmed/19275634
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