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The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimer’s Disease

Low-density lipoprotein receptor related protein-1 (LRP) is a member of the low-density lipoprotein (LDL) receptor family which has been linked to Alzheimer’s disease (AD) by biochemical and genetic evidence. Levels of neurotoxic amyloid -peptide (Aβ) in the brain are elevated in AD contributing to...

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Main Authors: Deane, R., Sagare, A., Zlokovic, B.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895311/
https://ncbi.nlm.nih.gov/pubmed/18673201
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