SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

Amyloid β-peptide (Aβ) deposition in cerebral vessels contributes to cerebral amyloid angiopathy (CAA) in Alzheimer’s disease (AD). Here, we report that in AD patients and two mouse models of AD, overexpression of serum response factor (SRF) and myocardin (MYOCD) in cerebral vascular smooth muscle c...

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Detaylı Bibliyografya
Asıl Yazarlar: Bell, Robert D., Deane, Rashid, Chow, Nienwen, Long, Xiaochun, Sagare, Abhay, Singh, Itender, Streb, Jeffrey W., Guo, Huang, Rubio, Anna, Van Nostrand, William, Miano, Joseph M., Zlokovic, Berislav V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654279/
https://ncbi.nlm.nih.gov/pubmed/19098903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1819
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