Differential Neuroprotection and Risk for Bleeding From Activated Protein C With Varying Degrees of Anticoagulant Activity

Por Wang, Yaoming, Thiyagarajan, Meenakshisundaram, Chow, Nienwen, Singh, Itender, Guo, Huang, Davis, Thomas P., Zlokovic, Berislav V.
Publicado em 2008

Species-dependent neuroprotection by activated protein C mutants with reduced anticoagulant activity

Por Guo, Huang, Wang, Yaoming, Singh, Itender, Liu, Dong, Fernández, José A., Chow, Nienwen, Zlokovic, Berislav V.
Publicado em 2009

Species-specific anticoagulant and mitogenic activities of murine protein S

Por Fernández, José A., Heeb, Mary J., Xu, Xiao, Singh, Itender, Zlokovic, Berislav V., Griffin, John H.
Publicado em 2009

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging

Por Bell, Robert D., Winkler, Ethan A., Sagare, Abhay P., Singh, Itender, LaRue, Barb, Deane, Rashid, Zlokovic, Berislav V.
Publicado em 2010

A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage

Por Aum, Diane J., Vellimana, Ananth K., Singh, Itender, Milner, Eric, Nelson, James W., Han, Byung Hee, Zipfel, Gregory J.
Publicado no Sci Rep (2017)

A Lipoprotein Receptor Cluster IV Mutant Preferentially Binds Amyloid-β and Regulates Its Clearance from the Mouse Brain

Por Sagare, Abhay P., Bell, Robert D., Srivastava, Alaka, Sengillo, Jesse D., Singh, Itender, Nishida, Yoichiro, Chow, Nienwen, Zlokovic, Berislav V.
Publicado em 2013

Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity

Por Guo, Huang, Singh, Itender, Wang, Yaoming, Deane, Rashid, Barrett, Theresa, Fernández, José A., Chow, Nienwen, Griffin, John H., Zlokovic, Berislav V.
Publicado em 2009

Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor

Por Zhu, Donghui, Wang, Yaoming, Singh, Itender, Bell, Robert D., Deane, Rashid, Zhong, Zhihui, Sagare, Abhay, Winkler, Ethan A., Zlokovic, Berislav V.
Publicado em 2010

Impairment of Glymphatic Pathway Function Promotes Tau Pathology after Traumatic Brain Injury

Por Iliff, Jeffrey J., Chen, Michael J., Plog, Benjamin A., Zeppenfeld, Douglas M., Soltero, Melissa, Yang, Lijun, Singh, Itender, Deane, Rashid, Nedergaard, Maiken
Publicado no J Neurosci (2014)

Minocycline protects against delayed cerebral ischemia after subarachnoid hemorrhage via matrix metalloproteinase‐9 inhibition

Por Vellimana, Ananth K., Zhou, Meng‐Liang, Singh, Itender, Aum, Diane J., Nelson, James W., Harris, Glenn R., Athiraman, Umeshkumar, Han, Byung H., Zipfel, Gregory J.
Publicado no Ann Clin Transl Neurol (2017)

Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells

Por Reynolds, Matthew R., Singh, Itender, Azad, Tej D., Holmes, Brandon B., Verghese, Phillip B., Dietrich, Hans H., Diamond, Marc, Bu, Guojun, Han, Byung Hee, Zipfel, Gregory J.
Publicado no Mol Neurodegener (2016)

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance

Por Singh, Itender, Sagare, Abhay P., Coma, Mireia, Perlmutter, David, Gelein, Robert, Bell, Robert D., Deane, Richard J., Zhong, Elaine, Parisi, Margaret, Ciszewski, Joseph, Kasper, R. Tristan, Deane, Rashid
Publicado em 2013

SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

Por Bell, Robert D., Deane, Rashid, Chow, Nienwen, Long, Xiaochun, Sagare, Abhay, Singh, Itender, Streb, Jeffrey W., Guo, Huang, Rubio, Anna, Van Nostrand, William, Miano, Joseph M., Zlokovic, Berislav V.
Publicado em 2008

Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

Por Han, Byung Hee, Zhou, Meng-liang, Johnson, Andrew W., Singh, Itender, Liao, Fan, Vellimana, Ananth K., Nelson, James W., Milner, Eric, Cirrito, John R., Basak, Jacob, Yoo, Min, Dietrich, Hans H., Holtzman, David M., Zipfel, Gregory Joseph
Publicado no Proc Natl Acad Sci U S A (2015)

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Por Deane, Rashid, Singh, Itender, Sagare, Abhay P., Bell, Robert D., Ross, Nathan T., LaRue, Barbra, Love, Rachal, Perry, Sheldon, Paquette, Nicole, Deane, Richard J., Thiyagarajan, Meenakshisundaram, Zarcone, Troy, Fritz, Gunter, Friedman, Alan E., Miller, Benjamin L., Zlokovic, Berislav V.
Publicado em 2012

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

Por Zhong, Zhihui, Ilieva, Hristelina, Hallagan, Lee, Bell, Robert, Singh, Itender, Paquette, Nicole, Thiyagarajan, Meenakshisundaram, Deane, Rashid, Fernandez, Jose A., Lane, Steven, Zlokovic, Anna B., Liu, Todd, Griffin, John H., Chow, Nienwen, Castellino, Francis J., Stojanovic, Konstantin, Cleveland, Don W., Zlokovic, Berislav V.
Publicado em 2009