Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

Cerebral amyloid angiopathy (CAA) is characterized by deposition of amyloid β peptide (Aβ) within walls of cerebral arteries and is an important cause of intracerebral hemorrhage, ischemic stroke, and cognitive dysfunction in elderly patients with and without Alzheimer’s Disease (AD). NADPH oxidase-...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Han, Byung Hee, Zhou, Meng-liang, Johnson, Andrew W., Singh, Itender, Liao, Fan, Vellimana, Ananth K., Nelson, James W., Milner, Eric, Cirrito, John R., Basak, Jacob, Yoo, Min, Dietrich, Hans H., Holtzman, David M., Zipfel, Gregory Joseph
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345564/
https://ncbi.nlm.nih.gov/pubmed/25675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414930112
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