Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice

Cerebral amyloid angiopathy (CAA) is characterized by deposition of amyloid β peptide (Aβ) within walls of cerebral arteries and is an important cause of intracerebral hemorrhage, ischemic stroke, and cognitive dysfunction in elderly patients with and without Alzheimer’s Disease (AD). NADPH oxidase-...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Han, Byung Hee, Zhou, Meng-liang, Johnson, Andrew W., Singh, Itender, Liao, Fan, Vellimana, Ananth K., Nelson, James W., Milner, Eric, Cirrito, John R., Basak, Jacob, Yoo, Min, Dietrich, Hans H., Holtzman, David M., Zipfel, Gregory Joseph
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345564/
https://ncbi.nlm.nih.gov/pubmed/25675483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414930112
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