Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy

BACKGROUND: Cerebral amyloid angiopathy (CAA) is characterized by deposition of fibrillar amyloid β (Aβ) within cerebral vessels. It is commonly seen in the elderly and almost universally present in patients with Alzheimer's Disease (AD). In both patient populations, CAA is an independent risk...

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Huvudupphovsmän: Han, Byung Hee, Zhou, Meng-liang, Vellimana, Ananth K, Milner, Eric, Kim, David H, Greenberg, Jacob K, Chu, Wenhua, Mach, Robert H, Zipfel, Gregory J
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259047/
https://ncbi.nlm.nih.gov/pubmed/22192811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-86
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