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Cerebral amyloid angiopathy increases susceptibility to infarction following focal cerebral ischemia in Tg2576 mice

We and others have shown that soluble amyloid-β peptide (Aβ) and cerebral amyloid angiopathy (CAA) cause significant cerebrovascular dysfunction in mutant amyloid precursor protein (APP) mice, and that these deficits are greater in aged APP mice having CAA compared to young APP mice lacking CAA. Aβ...

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Detalles Bibliográficos
Publicado en:Stroke
Main Authors: Milner, Eric, Zhou, Meng-liang, Johnson, Andrew W., Vellimana, Ananth K., Greenberg, Jacob K., Holtzman, David M., Han, Byung Hee, Zipfel, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288816/
https://ncbi.nlm.nih.gov/pubmed/25190447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.006078
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